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Neglected tropical

Ascariasis

An infection that is caused by the roundworm Ascaris lumbricoides, many cases of which remain asymptomatic. During the transient larval migratory phase, shortness of breath, fever, and eosinophilia can occur. Depending on the intestinal worm burden, a spectrum of gastrointestinal tract symptoms can occur.

Balanced: 85th of 142Biggest burden: 117th of 142Most neglected: 40th of 142

Starter kit · coming soon

Start building on ascariasis

See a finished example: the malaria starter kit →

Where the field stands

  1. 01

    Early understanding

    No strong gene target or drug candidate yet

  2. 02

    Target found

    At least one gene target with strong evidence

  3. 03

    Drug candidates

    Preclinical or phase 1 drug candidates

  4. 04

    In trials

    Drug candidates in phase 2 or later

  5. 05

    Has approved drugs

    At least one approved drug; not necessarily a cure

Derived from Open Targets drug and target data, not self-reported.

Healthy years lost (DALYs), 2023

803k

95% range 588k to 1.1M

Deaths, 2023

5k

People living with it, 2023

338.4M

GBD cause: Ascariasis (exact match)

Research attention

Active clinical trials

2

All clinical trials, ever

13

Papers published, 2025

53

Active trials per million healthy years lost

2.5

Lower means fewer trials for the size of the problem

What there is to build on

Open Targets Platform ↗

Gene targets with strong evidence

0

of 49 associated genes

Top associated genes

IGHECD40LGCD79ACA2CA1

Drugs and clinical candidates

6

Approved drugs

1

Identifiers

Open Targets
MONDO_0005654
ICD-10
B77

Trial and paper counts are rough measures of attention, not of progress. This page is for research planning, not medical advice.